Dr. Baggerly and colleagues at MD Anderson in Houston, Texas tried to reproduce the findings Drs. Nevins and Potti described in their seemingly groundbreaking papers.

However, they quickly realized that there were many, many problems with that work. Nonetheless, they persevered, in large part because the promises the work made were so exciting and potentially life-saving.

Unfortunately, the work turned out to be based on errors and possibly even fraud.

To understand how they learned the truth, watch these two lectures, given years apart.

(1)

The Importance of Reproducible Research in High-Throughput Biology: Case Studies in Forensic Bioinformatics

This is video of a lecture given in 2010 at Cancer Bioinformatics Workshop, Cambridge 2010 .

(2)

Keith Baggerly: Importance of Reproducibility in High-Throughput Biology

This was an on-line lecture given in March of 2020.